VANCOUVER, British Columbia and SAN DIEGO – AbCellera (Nasdaq: ABCL) and Empirico Inc. (“Empirico”) announced today that they have entered into a strategic multi-target discovery collaboration. Through each company’s proprietary technologies, the multi-target collaboration leverages hyper-scale datasets, machine learning, and advanced computation to both identify high-value, genetically-validated drug targets and discover novel therapeutic antibodies. Empirico will use its Precision Insights Platform, a human genetics-focused discovery platform, to select up to five therapeutic targets. AbCellera will use its AI-powered antibody discovery technology to search and analyze natural immune responses to identify antibodies with the desired therapeutic properties against the selected targets.
Under the terms of the agreement, Empirico will have the rights to develop and commercialize novel antibodies resulting from the collaboration. AbCellera will receive research payments and is eligible to receive downstream clinical and commercial milestone payments and royalties on net sales of products from Empirico.
“One of the biggest challenges in drug development is the lack of translation between preclinical models and human disease. Empirico’s platform seeks to overcome this hurdle by uncovering causal relationships between human genetic variation and clinical outcomes to discover and validate targets,” said Carl Hansen, Ph.D., CEO and President of AbCellera. “We are excited to partner with Empirico and serve as its operating system for developing new antibody-based therapies against genetically-validated targets.”
“Using our Precision Insights Platform, Empirico has discovered multiple genetically-validated targets for diseases with unmet medical need, several of which are amenable to modulation with therapeutic antibodies,” said Omri Gottesman, M.D., CEO and President of Empirico. “For these and future programs, our partnership with AbCellera empowers and enables us to rapidly translate therapeutic insights from human genetics into potential new medicines for patients in need.”
About Empirico Inc.
Empirico is a next-generation therapeutics company founded on utilizing human genetics, data science and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform, a proprietary human genetics-focused discovery platform, leverages a world-leading dataset, hyperscale infrastructure and algorithmic approaches that encode and enhance human intuition to identify and prioritize therapeutic targets. All potential therapeutic targets are subjected to rigorous in vitro and in vivo experimental validation to elucidate the mechanism by which genetic variation impacts disease risk and provide insights about which therapeutic modality could be ‘programmed’ to mimic or interfere with that mechanism. Empirico is advancing multiple preclinical programs across a broad range of indications and therapeutic modalities, both independently and in collaboration with industry partners. Empirico is headquartered in San Diego, Calif. with laboratories in Madison, Wis. To learn more about Empirico, visit www.empiricotx.com.
About AbCellera Biologics Inc.
AbCellera is a technology company that searches, decodes, and analyzes natural immune systems to find antibodies that its partners can develop into drugs to prevent and treat disease. AbCellera partners with drug developers of all sizes, from large pharmaceutical to small biotechnology companies, empowering them to move quickly, reduce cost, and tackle the toughest problems in drug development. abcellera.com.
AbCellera Forward-looking Statements
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Source: AbCellera Biologics Inc.
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