AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.
We are seeking a highly motivated Research Scientist to implement in-silico structural tools and processes in the areas of protein and antibody engineering. You will interact with a diverse team, liaising between software engineers, wet-lab scientists, bioinformaticians and data scientists, in a fast-paced environment. You are someone who is able to multitask, problem-solve, think critically, and demonstrate scientific rigor, and above all, you are someone who can learn and grow with us.
This is an exciting opportunity to join one of Canada’s most innovative biotech companies and to contribute to our cutting-edge research, driving the discovery of novel monoclonal antibodies for therapeutic use.
How you might spend your days:
- Designing, implementing, and evaluating in-silico protein engineering activities in support of a developing platform for antibody reformatting processes and optimization of therapeutic assets
- Collaborating with teams across the company to understand engineering challenges and propose solutions
- Preparing and authoring materials to educate colleagues, and communicate strategies, key findings, and implications
- Organizing, supporting, and collaborating with other team members to meet project deliverables and timelines
We’d love to hear from you if:
- You are a collaborative team player that can contribute to the design, execution, and evaluation of in-silico protein engineering workflows
- You are excited about the opportunity to integrate high throughput protein engineering methods with in-silico tools to solve real-world drug discovery problems
- You are enthusiastic about applying your expertise in protein engineering to improve the speed and quality of protein biotherapeutics development
- You are strongly self-motivated and work independently to identify project needs and follow that up with building and implementing solutions
- You have a PhD in Biochemistry, Biophysics, Structural Biology, Computational Biology, Computer Science, or a related field, or a MSc with 5+ years of related experience in a biological research setting
- You have excellent programming skills in Python, as well as a comprehensive understanding of techniques to perform in-silico protein structure design using tools such as Rosetta software suite
- You have working knowledge of antibody structure and function, and familiarity with techniques applicable to the molecular design, engineering, and experimental evaluation of antibody and/or antigen libraries for protein engineering purposes
- You have awareness of experimental analytic and biophysics techniques used for antibody characterization, e.g. size exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), capillary electrophoresis (CE), light scattering (DLS, MALS), differential scanning calorimetry (DSC), isoelectric focusing (IEF), surface plasmon resonance (SPR), etc.
What we offer:
AbCellera’s hiring range for this role is CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.
You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera.
About AbCellera:
AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.
And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.
We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.
To apply:
Please submit your application through our website and refer to Job ID 23231 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.
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