April 15, 2024 Job ID: 23194

AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.

We are seeking a highly motivated Research Scientist with a background in both protein purification and antibody drug conjugate (ADC) development to join our multidisciplinary team. This lab-based position is a great opportunity to help build ADC production and conjugation workflows and progress our ADC therapeutic candidates.  Our ideal candidate is a highly motivated and self-directed individual, a team-player who thrives in a fast-paced work environment with multiple competing priorities, and above all, someone who can learn and grow with us. This role offers the exciting opportunity to join one of Canada’s top biotech companies, while growing with a team that believes in collaboration, innovation, and mutual support.

How you might spend your days

  • Developing and optimizing workflows for ADC conjugation and purification, and initiating process scaling studies for ADC production
  • Designing and performing DOE assays for screening ADC conjugation scouting, buffer formulation and product characterization
  • Assessing critical quality attributes of the ADC candidates by establishing and implementing assays that assess product stability and homogeneity, including but not limited to: aSEC, icIEF, CE-SDS, HIC and other HPLC characterization assays
  • Executing and validating emerging technologies in the field of conjugate science and ADC therapeutic discovery
  • Collaborating with teams across the company to solve problems, analyze, interpret and communicate data 
  • Training and mentoring more junior scientists
  • Growing your technical skill set and engaging in professional development
  • Preparing and authoring materials to educate colleagues as well as communicate strategies, key findings and implications 

We'd love to hear from you if

  • You have demonstrated hands-on experience with conjugation and purification of antibody-drug conjugates, preferably in an industry setting
  • You enjoy a fast-paced work environment and are a creative problem solver who believes in teamwork to tackle the most challenging problems
  • You hold a PhD in Biochemistry, Biological Chemistry, Chemistry or a related field, with 2-3 years of antibody or other protein conjugation experience; candidates with a MSc and 4-8 years of relevant experience, including 2-3+ years of experience specifically with ADCs in an industry setting, will also be considered
  • You have a working knowledge of antibody structure and function, as well as modern antibody linker technologies
  • You are comfortable working independently and escalating concerns with project execution and deliverables
  • You are excited about the opportunity to develop and optimize cutting edge antibody drug conjugates 
  • You have exceptional analytical and problem-solving capabilities, as well as excellent verbal and written communication skills including public presentation of complex data
  • You have strong interpersonal skills with the ability to work collaboratively as a member of cross-functional team

What we offer

AbCellera’s hiring range for this role is CAD $93,300 - 116,700 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. 

We have a number of ways to support AbCellerites in maximizing their work-life synergy. You will have a $1,500 annual Active Lifestyle Allowance, annual vacation, the opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find abundant teams and social groups to build community and connections across AbCellera.

About AbCellera

AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.

We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success. 

To apply

Please submit your application through our website and refer to Job ID 23194 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.