Molecular Biology & NGS

We focus on sequencing, expressing, and characterizing antibodies from discovery screens. Using next-generation sequencing technologies, we generate large libraries of antibody sequences from individual cells recovered from our customized screening platform. We generate even larger libraries from bulk-sequenced samples of immune repertoires and overlay our single cell sequences to predict heavy and light chain pairings, amplifying our antibody pool and diversity. We use these sequences to express, characterize, and validate antibodies to narrow down the most robust and promising antibody leads for development.